The Silk Industry's Digital Leap: Sericulture 4.0
DOI:
https://doi.org/10.55938/wlp.v1i4.166Keywords:
Digitization, Silk Fibroin (SF), 3D Printing Inks, Photo-Crosslinking, Bio-Ink, Polymer HydrogelsAbstract
The association between Sericultural digitalization, farmer enrichment, and agricultural growth is complicated and varied, with population aging, industrialization, government backing, and resident capability all playing important roles. Policies should take spatial implications into account when designing and implementing them. Income disparities, the elderly population, and financial self-sufficiency are all key factors. Differentiated, accurate, and integrated management policies may be devised to aid in the planning, building, and management of digital Sericulture and smart settlements. This method has the potential to assist rural communities overcome their issues and foster long-term development. Hydrogels have acquired popularity in tissue engineering and regenerative medicine because of their biocompatibility, adjustable breakdown, and low immunogenicity. This study explores the chemical functionalization options for Silk Fibroin (SF) materials, as well as their physical features. It discusses various functionalization methods, cross-linking concepts, and the potential and limitations of methacrylate compound functionalization. The paper also examines functional SF hydrogels and their applications in bio-fabrication, tissue engineering, and regenerative medicine. The recommendations are intended to help in the future development of SF hydrogels and composites. This study investigates the composition, structure, characteristics, and activities of silk proteins, as well as their significance in 3D in vitro models and current breakthroughs in medicinal applications. It emphasizes the physiological properties of silk matrix ingredients in in vitro tissue constructions, as well as current research problems and complications, with the goal of developing complex and biomimetic silk protein-based micro-tissues. Multiple photo-crosslinking techniques have been used on modified silk fibroin, resulting in a novel method for light-based crosslinking and micro-fabrication. The molecular design properties of silk fibroin inks, as well as the photo-crosslinking methods, indicate that they may have future biological applications.
References
Lai, M., Li, W., Gao, Z., & Xing, Z. (2024). Evaluation, mechanism and policy implications of the symbiotic relationship among rural digitization, agricultural development and farmer enrichment: evidence from digital village pilots in China. Frontiers in Environmental Science, 12, 1361633.
Stuart-Fox, D., Ng, L., Barner, L., Bennett, A. T., Blamires, S. J., Elgar, M. A., ... & Wong, W. W. (2023). Challenges and opportunities for innovation in bioinformed sustainable materials. Communications Materials, 4(1), 80.
Kwak, H. W., Ju, J. E., Shin, M., Holland, C., & Lee, K. H. (2017). Sericin promotes fibroin silk I stabilization across a phase-separation. Biomacromolecules, 18(8), 2343-2349.
Teramoto, H., Kojima, K., Iga, M., & Yoshioka, T. (2023). Unique Material Properties of Bombyx mori Silk Fiber Incorporated with 3-Azidotyrosine. Biomacromolecules, 24(9), 4208-4217.
Bhowmik, P., Kant, R., & Singh, H. (2023). Effect of degumming duration on the behavior of waste filature silk-reinforced wheat gluten composite for sustainable applications. ACS omega, 8(7), 6268-6278.
Hu, Y., Zou, Y., Ma, Y., Yu, J., Liu, L., Chen, M., ... & Fan, Y. (2022). Formulation of silk fibroin nanobrush-stabilized biocompatible pickering emulsions. Langmuir, 38(46), 14302-14312.
Zheng, X., Zhao, M., Zhang, H., Fan, S., Shao, H., Hu, X., & Zhang, Y. (2018). Intrinsically fluorescent silks from silkworms fed with rare-earth upconverting phosphors. ACS Biomaterials Science & Engineering, 4(12), 4021-4027.
Mu, X., Sahoo, J. K., Cebe, P., & Kaplan, D. L. (2020). Photo-crosslinked silk fibroin for 3D printing. Polymers, 12(12), 2936.
Amirian, J., Wychowaniec, J. K., Amel Zendehdel, E., Sharma, G., Brangule, A., & Bandere, D. (2023). Versatile Potential of Photo-Cross-Linkable Silk Fibroin: Roadmap from Chemical Processing Toward Regenerative Medicine and Biofabrication Applications. Biomacromolecules, 24(7), 2957-2981.
Das, S., Jegadeesan, J. T., & Basu, B. (2024). Gelatin Methacryloyl (GelMA)-Based Biomaterial Inks: Process Science for 3D/4D Printing and Current Status. Biomacromolecules, 25(4), 2156-2221.
Shuai, Y., Zheng, M., Kundu, S. C., Mao, C., & Yang, M. Bioengineered Silk Protein‐Based 3D In Vitro Models for Tissue Engineering and Drug Development: From Silk Matrix Properties to Biomedical Applications. Advanced Healthcare Materials, 2401458.
Tan, X. H., Liu, L., Mitryashkin, A., Wang, Y., & Goh, J. C. H. (2022). Silk fibroin as a bioink–a thematic review of functionalization strategies for bioprinting applications. ACS Biomaterials Science & Engineering, 8(8), 3242-3270.
Gamboa, J., Paulo-Mirasol, S., Estrany, F., & Torras, J. (2023). Recent progress in biomedical sensors based on conducting polymer hydrogels. ACS applied bio materials, 6(5), 1720-1741.
Liu, C., Kim, J. T., Yang, D. S., Cho, D., Yoo, S., Madhvapathy, S. R., ... & Rogers, J. A. (2023). Multifunctional Materials Strategies for Enhanced Safety of Wireless, Skin‐Interfaced Bioelectronic Devices. Advanced Functional Materials, 33(34), 2302256.
Geiger, S., Michon, J., Liu, S., Qin, J., Ni, J., Hu, J., ... & Lu, N. (2020). Flexible and stretchable photonics: the next stretch of opportunities. ACS Photonics, 7(10), 2618-2635.
Zou, M., Li, S., Hu, X., Leng, X., Wang, R., Zhou, X., & Liu, Z. (2021). Progresses in tensile, torsional, and multifunctional soft actuators. Advanced Functional Materials, 31(39), 2007437.
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Copyright (c) 2025 Shailender Thapliyal, Saravanan P
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